Pediatric Bone Marrow Transplant

Advanced Infrastructure Excelling in Bone Marrow Transplant

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A bone marrow transplant (BMT) or stem cell transplant is a transformative therapy for children suffering with certain cancers, blood and immune disorders. Pediatric blood disorders, while not always malignant, can significantly compromise a child’s quality of life and in certain cases pose a serious threat to their survival. The ultimate goal of this life saving Bone Marrow or Hematopoietic Stem Cell Transplant involves the infusion of healthy blood-stem cells into the body to replace diseased or damaged bone marrow.

At Rainbow Children’s Hospitals, our expert Haematology team employs cutting-edge techniques to provide appropriate bone marrow transplant treatments, ensuring optimal outcomes for each child, who requires it.

Types of Bone Marrow Transplants:

At Rainbow Children’s Hospital, we provide below types of Bone Marrow or Stem Cell or Hematopoietic Cell Transplants:

Hematopoietic Cell Transplants:

1. Autologous Bone Marrow Transplants:

An Autologous bone marrow or stem cell transplant involves harvesting healthy stem cells from the patient’s own body to restore the bone marrow’s ability to produce blood cells. This type of BMT is used in the treatment of certain high-risk cancers and autoimmune disorders. It carries a lower risk of graft-versus-host disease, as the transplanted cells originate from the patient itself.

2. Allogeneic Bone Marrow Transplants

Allogeneic bone marrow or stem cell transplants involve the use of stem cells from a healthy donor. This type of transplants is required for treating many genetic blood disorders, high-risk blood cancers and other genetic disorders as well. Allogeneic transplant can be from matched related donor or matched unrelated donor and Haploidentical type, based on donor availability. This type of transplants may possess graft-versus-tumour effect in case of cancers.

Haploidentical Transplant is a type of allogeneic stem cell transplant that uses partially matched family donor (a close family member like a parent, child, or sibling), thus expands donor options for patients. This option is ideal when a fully matched donor is not available.

Cord Blood Stem Cell Transplantation:

A Cord blood stem cell transplantation using stem cells from umbilical cord blood is an option for patients without matched donors. These stem cells, collected immediately after birth, possess a remarkable capacity to differentiate into mature, functional blood cells more rapidly and efficiently than stem cells obtained from the bone marrow of a child or adult.

If you or a loved one is facing cancer or a serious blood disease, a stem cell transplant might offer a new chance at recovery. For some people, it can lead to long-term remission or even a cure—especially when other treatments haven’t worked.

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Dr. Sirisha Rani

Sr. Consultant- Pediatric Hematologist & Oncologist, BMT..

  • English, Hindi, Kannada, Tamil, Telugu
  • Banjara Hills, Currency Nagar, Health City

Dr. Vasudha N R

Consultant- Pediatric Hematologist, Oncologist & BMT Physici..

  • English, Kannada, Marathi, Telugu
  • Marathahalli, Hebbal

Dr. Meena Sivasankaran

Consultant - Pediatric Hemato Oncology..

  • English, Hindi, Tamil
  • Guindy

Dr. Nalla Anuraag Reddy

Consultant Pediatric Hematologist, Oncologist, Blood & Marro..

  • English, Hindi, Kannada, Tamil, Telugu
  • Banjara Hills, Hydernagar, Financial District

Dr. Nandini Choudhury Hazarika

Consultant - Medical Oncology, BMT..

  • English, Hindi
  • Malviya Nagar

Dr. Sandhya Vaddadi

Consultant Hematology & Oncology, BMT..

  • English, Hindi, Kannada, Telugu
  • Secunderabad, Banjara Hills, Currency Nagar

Dr. Manojit Chakraborty

Consultant - Paediatric Hematology, Oncology & Bone Marrow T..

  • Assamese, Bengali, English, Hindi, Kannada, Marathi
  • Marathahalli, Bannerghatta, Sarjapur Road, Guwahati

A bone marrow transplant may be required in patients whose bone marrow has been severely damaged by disease, infections, or chemotherapy. This treatment offers hope to children from a range of serious conditions including

  • Childhood anemia
  • Iron deficiency anemia
  • Iron-refractory iron deficiency anemia
  • Congenital sideroblastic anemia
  • Congenital dyserythropoietic anemia

Additionally, BMT provides significant therapeutic benefits for children diagnosed with certain types of cancer and blood disorders, such as sickle cell disease, leukemia, and thalassemia.

Every child’s situation is unique. At Rainbow Children’s Hospital, one of the best pediatric bone marrow transplant hospital, our expert team carefully evaluates your child’s overall health, type of disease, previous treatments, and other important factors to determine whether a stem cell transplant is the right option.

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Patient Stories

Embark on a journey of inspiration and hope with our patient success stories

Second Chance at Life

A Life-Saving Bone Marrow Transplant Journey

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Patient testimonial for Dr. Manojit Chakraborty, Consultant at Rainbow Children’s Hospitals, Paediatric Hematology, Oncology & Bone Marrow Transplant, praised as a really good doctor.
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Why Choose Us?

Rainbow Group operates a well-established network of 21 hospitals and 5 clinics across India, with a total bed capacity of 2185 beds exclusively to Pediatric and Women’s care. The Group offers comprehensive services in Pediatrics, Maternity, Gynecology, and Fertility Care.

Pediatric services, offered under the brand Rainbow Children’s Hospital, cover a wide range of pediatric super specialties, including robust neonatal and pediatric intensive care, multi-specialty pediatric services, and advanced quaternary care, such as pediatric organ transplantation. For over 26 years, Rainbow Children’s Hospital (RCH) has been at the forefront of transforming pediatric healthcare in India and has grown to become the largest multi- specialty pediatric hospital group in the country. Rainbow Children’s Hospital built on strong fundamentals of a multidisciplinary approach with a full-time consultant led clinical service along with 24/7 commitment in a child centric environment. With a strong focus on improving quality, clinical outcomes, and delivering seamless, comprehensive care across all pediatric specialties- RCH has established itself as a leader in child-centric healthcare. Our hospitals are staffed with highly qualified professionals and designed to provide the best possible environment for children and their families.

  • Over 26 Years of Trust
  • Largest level IV NICU (Neonatal Intensive Care Unit) Network in the Country
  • Full Spectrum of Pediatric Super Specialities
  • Multidisciplinary Pediatric Team
  • 24/7 Inhouse Consultant Availability
  • Child Friendly Infrastructure
  • Access to Experienced Clinical Team
  • Specialized Pediatric Emergency Care

At Rainbow Children’s Hospital & BirthRight by Rainbow Hospitals, we are committed to upholding international standards in pediatric, neonatal, and maternity care. Our International Patient Services are designed to ensure a seamless healthcare journey — from your first inquiry to post-treatment follow-up.

Fertility services under the brand name BirthRight Fertility, have emerged not only as a fertility center but as a ray of hope for couples aspiring to embrace parenthood. Within the confines of our facility, technology and compassion intertwine seamlessly. Our Fertility units, nestled within Rainbow Children’s Hospital, boasts state-of-the-art equipment and a suite of diagnostic tools that ensure the precision and accuracy integral to each diagnosis and treatment plan. Here, our experts stand as pillars of support, navigating the intricate paths of fertility treatments with empathy and expertise. What sets us apart is our pursuit of excellence, a commitment that has earned us the coveted accreditation by the Joint Commission International (JCI) for our Kondapur unit. This recognition is evidence to our dedication to quality, safety, and patient-centric care. It is an embodiment of the trust and confidence that couples from all walks of life place in us.

FAQ’s

What is a pediatric bone marrow transplant?

Pediatric Bone Marrow Transplantation is a medical procedure that replaces damaged or diseased bone marrow with healthy stem cells to restore normal blood cell production in children.

Why is a bone marrow transplant needed?

Bone marrow transplant is needed to treat conditions like leukemia, lymphoma, severe anemia, immune deficiencies, or certain genetic disorders.

What is the typical duration of the bone marrow transplant procedure?

The overall duration of treatment varies depending on the underlying condition and type of transplant. Pre-Transplant preparation may take 2 weeks to 2 months. The transplant procedure itself requires hospitalization for a minimum of 4 weeks. Following the transplant, intensive follow-up care is typically necessary for 3 to 6 months, with total follow-up extending over a period of 1 to 2 years to monitor recovery and long-term outcomes.

Is bone marrow transplant safe for children?

Bone marrow or Hematopoietic stem cell transplant is curative for children suffering with high risk cancers and is the only available cure for genetic disorders like Thalassemia, Sickle cell anemia and other transfusion dependent anaemias, Bone marrow failure syndromes, Metabolic disorders like Gauchers disease, Mucopolysaccahridosis, Immunodeficiency disorders etc. Specialized conditioning regimens and treatment protocols are followed for BMT in children to ensure safety and best outcomes.

What is the success rate of bone marrow transplant in children?

Success rate for BMT depends on certain factors like availability of full match donor, underlying disease and the general condition of the child undergoing transplant. BMT success rate is better in children compared to adults as most children do not have many co-morbidities and can vary from 75% to more than 95%.

What is the youngest age for a bone marrow transplant?

For certain genetic disorders like severe immunodeficiency and high-risk blood cancers, BMT is an emergency and needs to be done as soon as possible even during infancy. For most other conditions, usually BMT is done after 1-year age.

Is bone marrow transplant painful?

The bone marrow transplant procedure per se is not painful for the child.

What are the potential side effects of bone marrow transplants?

The potential side effects include: Related to chemotherapy –conditioning, Loss of hair/ skin pigmentation, Mouth ulcers/Bleeding, Infections-viral/bacterial/fungal, Engraftment syndrome, Veno-occlusion, Immune mediated Problems, Graft Versus Host disease. Majority of these conditions are manageable with appropriate therapies.

How long is the recovery period after a bone marrow transplant?

Recovery period is usually 6 months to 1 year.

Can my child attend school or normal activities after transplant?

Children need time to recover their immune system before returning to school; this varies by individual and doctor’s advice.

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